Lymphatic transport of plutonium from subcutaneous tissue in rats.

Lymphatic transport and catabolism of therapeutic proteins after subcutaneous administration to rats and dogs.

The mechanism underlying subcutaneous absorption of macromolecules and factors that can influence this process were studied in rats using PEGylated erythropoietins (EPOs) as model compounds. Using a thoracic lymph duct cannulation (LDC) model, we showed that PEGylated EPO was absorbed from the subcutaneous injection site mainly via the lymphatic system in rats, which is similar to previous repo...

Lymphatic Transport and Catabolism of Therapeutic Proteins Following Subcutaneous Administration to Rats and Dogs

Perlipin a Protein of Subcutaneous Adipose Tissue and Pancreatic Bcells Function in Diabetic Rats

Objective: The aim of this study was to compare the three endurance training intensities on the expression of Perlipin A protein in subcutaneous adipose tissue and pancreatic B-cells function in male diabetic rats. Materials and Methods: In this study, 40 healthy male wistar rats were divided into five groups, including diabetic with low intensity endurance training, diabetic with moderate int...

Transdiaphragmatic Lymphatic Transport of Intraperitoneally Administered Markers in Rats

Experimental studies were undertaken, aiming at evaluation of lymphatic drainage from the peritoneal cavity to lymph nodes of the cranial mediastinum in rats. The study made use of 11 adult male Wistar rats. For examination of lymphatic structures drawing ink and FITC-dextran, administered intraperitoneally, were used. Due to lack of unambiguous terminology quoted in the literature with regard ...

Biocompatibility of acetazolamide pastes in the subcutaneous tissue of rats.

This aim of this study was to investigate the biocompatibility of two experimental acetazolamide (AZ)-based pastes in the subcutaneous tissue of rats. Both pastes contained AZ as the main component in similar concentration. The vehicle in experimental paste 1 was saline, while experimental paste 2 was prepared with propylene glycol. Sixty polyethylene tubes were sealed at one end with gutta-per...